Jiankang Liu Selected Research

Thioctic Acid (Lipoic Acid)

1/2021	Htd2 deficiency-associated suppression of α-lipoic acid production provokes mitochondrial dysfunction and insulin resistance in adipocytes.
4/2014	Reloading functionally ameliorates disuse-induced muscle atrophy by reversing mitochondrial dysfunction, and similar benefits are gained by administering a combination of mitochondrial nutrients.
1/2010	Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease.
8/2009	The effect of acetyl-L-carnitine and R-alpha-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer's disease.
7/2008	Protective effects of R-alpha-lipoic acid and acetyl-L-carnitine in MIN6 and isolated rat islet cells chronically exposed to oleic acid.
1/2008	The effects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview.
6/2007	D-galactose toxicity in mice is associated with mitochondrial dysfunction: protecting effects of mitochondrial nutrient R-alpha-lipoic acid.
1/2007	Acrolein, a toxicant in cigarette smoke, causes oxidative damage and mitochondrial dysfunction in RPE cells: protection by (R)-alpha-lipoic acid.
8/2006	Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid.
6/2006	Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Jiankang Liu Research Topics

Disease

45	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 02/2002
21	Neoplasms (Cancer) 01/2022 - 01/2011
20	Insulin Resistance 02/2022 - 11/2009
19	Heart Failure 01/2022 - 08/2015
15	Hypertension (High Blood Pressure) 01/2021 - 03/2003
12	Cognitive Dysfunction 11/2021 - 02/2002
12	Obesity 01/2021 - 03/2003
11	Inflammation (Inflammations) 12/2021 - 01/2013
11	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2020 - 06/2008
10	Type 2 Diabetes Mellitus (MODY) 01/2021 - 01/2015
10	Neuroblastoma 07/2017 - 08/2006
9	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2008
8	Myocardial Infarction 01/2022 - 04/2011
8	Body Weight (Weight, Body) 01/2020 - 06/2008
7	Carcinogenesis 01/2022 - 12/2010
7	Parkinson Disease (Parkinson's Disease) 01/2021 - 07/2008
6	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 07/2010
6	Macular Degeneration (Age-Related Maculopathy) 01/2020 - 01/2007
5	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2021 - 10/2009
5	Stroke (Strokes) 01/2019 - 01/2010
4	Melanoma (Melanoma, Malignant) 01/2021 - 01/2014
4	Hyperlipidemias (Hyperlipidemia) 11/2020 - 10/2014
4	Necrosis 06/2018 - 06/2010
4	Coronary Disease (Coronary Heart Disease) 11/2017 - 06/2008
3	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 07/2013
3	Fatty Liver 12/2019 - 04/2014
3	Infections 12/2019 - 01/2018
3	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2019 - 01/2018
3	Myocardial Ischemia (Ischemic Heart Diseases) 01/2019 - 06/2012
3	Heart Arrest (Cardiac Arrest) 10/2018 - 03/2015
3	Non-alcoholic Fatty Liver Disease 03/2016 - 10/2014
3	Muscular Atrophy (Muscle Atrophy) 01/2016 - 05/2011
3	Colonic Neoplasms (Colon Cancer) 08/2014 - 01/2012
3	Memory Disorders (Memory Loss) 08/2006 - 02/2002
2	Stomach Neoplasms (Stomach Cancer) 03/2022 - 01/2015
2	Cardiomyopathies (Cardiomyopathy) 01/2022 - 06/2012
2	Dementia (Dementias) 01/2021 - 11/2011

Drug/Important Bio-Agent (IBA)

30	Proteins (Proteins, Gene)FDA Link 02/2022 - 02/2002
17	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 11/2006
15	EnzymesIBA 01/2022 - 02/2002
13	LipidsIBA 01/2021 - 08/2010
12	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2018 - 01/2010
11	Triglycerides (Triacylglycerol)IBA 01/2021 - 06/2008
11	Thioctic Acid (Lipoic Acid)IBA 01/2021 - 02/2002
11	3,4-dihydroxyphenylethanol (hydroxytyrosol)IBA 11/2016 - 12/2007
9	Insulin (Novolin)FDA Link 01/2020 - 11/2006
9	AntioxidantsIBA 01/2019 - 12/2007
9	Acrolein (Aqualin)IBA 03/2015 - 06/2006
8	LeptinIBA 03/2020 - 02/2006
7	HydrogenIBA 07/2022 - 01/2016
7	Retinal Pigments (Pigments, Visual)IBA 01/2020 - 01/2007
6	Olive OilIBA 01/2021 - 07/2010
6	Mineralocorticoid Receptor AntagonistsIBA 12/2020 - 01/2017
6	Spironolactone (Aldactone)FDA LinkGeneric 12/2020 - 01/2017
6	Acetylcarnitine (Alcar)IBA 04/2014 - 02/2002
6	Oxidants (Oxidizing Agents)IBA 05/2011 - 01/2007
5	Biomarkers (Surrogate Marker)IBA 03/2022 - 12/2010
5	punicalaginIBA 02/2022 - 10/2014
5	CytokinesIBA 01/2021 - 01/2014
5	sacubitril and valsartan sodium hydrate drug combinationIBA 01/2021 - 08/2015
5	AdiponectinIBA 03/2020 - 11/2011
5	Adenosine Triphosphate (ATP)IBA 12/2019 - 07/2008
4	CholesterolIBA 12/2020 - 10/2014
4	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 02/2002
4	Neprilysin (Neutral Endopeptidase)IBA 10/2018 - 11/2010
4	Galactose (Galactopyranose)FDA LinkGeneric 03/2014 - 06/2006
4	Pharmaceutical PreparationsIBA 02/2014 - 11/2009
4	HDL CholesterolIBA 01/2013 - 06/2008
3	Therapeutic UsesIBA 07/2022 - 06/2014
3	LipopolysaccharidesIBA 07/2022 - 01/2014
3	DiureticsIBA 01/2022 - 01/2016
3	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2022 - 10/2013
3	Enalapril FDA LinkGeneric 01/2021 - 08/2015
3	Hypoglycemic Agents (Hypoglycemics)IBA 01/2021 - 06/2008
3	Mitochondrial DNA (mtDNA)IBA 01/2021 - 02/2015
3	Ligases (Synthetase)IBA 10/2020 - 01/2016
3	UbiquitinIBA 10/2020 - 01/2010
3	Messenger RNA (mRNA)IBA 01/2020 - 07/2008
3	Malondialdehyde (Propanedial)IBA 01/2020 - 06/2006
3	PalmitatesIBA 12/2019 - 10/2014
3	Imiquimod (Aldara)FDA LinkGeneric 01/2019 - 01/2018
3	Amyloid (Amyloid Fibrils)IBA 12/2018 - 11/2016
3	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 05/2018 - 08/2015
3	Superoxides (Superoxide)IBA 04/2016 - 07/2013
3	ResveratrolIBA 01/2016 - 01/2016
3	CurcuminIBA 03/2014 - 11/2013
3	SmokeIBA 12/2010 - 01/2007
3	alpha-SynucleinIBA 04/2010 - 07/2008
2	Oxygen (Dioxygen)IBA 07/2022 - 01/2016
2	ORALIT (ORS)IBA 03/2022 - 06/2008
2	Dynamins (Dynamin)IBA 01/2022 - 12/2020
2	Deubiquitinating EnzymesIBA 01/2022 - 12/2020
2	Amyloid beta-PeptidesIBA 11/2021 - 11/2010
2	PotassiumIBA 01/2021 - 05/2018
2	LDL Lipoproteins (beta Lipoproteins)IBA 01/2021 - 01/2018
2	paragonIBA 01/2021 - 01/2021
2	omecamtiv mecarbilIBA 01/2021 - 12/2020
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2021 - 01/2020

Therapy/Procedure

17	Therapeutics 01/2022 - 12/2008
3	Mediterranean Diet 11/2016 - 07/2010